Similac^® Human Milk Fortifier

Extensively Hydrolyzed Protein Concentrated Liquid

(SHMF HP CL)

Nutrients	Per 5 mL SHMF HP CL packet	Per 30 mL* PTHM (25 mL) + SHMF HP CL (1 packet)	Per 100 mL PTHM (25 mL) + SHMF HP CL (1 packet)	Per 100 Cal^‡ PTHM (25 mL) + SHMF HP CL (1 packet)
Calories	7	24	79	100
Volume, mL	5	30	100	126
Protein, g	0.5	0.85^§	2.84	3.58
Fat, g	0.21	1.18	3.94	4.98
Carbohydrates, g	0.75	2.41^§	8.04	10.14
Water, g	3.3	25.3	84	106
Linoleic Acid, mg	18	110^†	368	464

Vitamins
Vitamin A, IU	197	295	982	1238
Vitamin D, IU	35	36	118	149
Vitamin E, IU	1	1.3	4.2	5.3
Vitamin K, mcg	2.4	2.5	8.2	10.3
Thiamin (Vit B1), mcg	48	53	177	224
Riboflavin (Vit B2), mcg	74	86	287	362
Vitamin B6, mcg	50	53	179	226
Vitamin B12, mcg	0.13	0.14	0.47	0.6
Niacin, mcg	980	1010	3392	4279
Folic Acid, mcg	7	8	26.1	32.9
Pantothenic Acid, mcg	310	355	1184	1494
Biotin, mcg	5.8	5.9^†	19.7	24.8
Vitamin C, mg	7.7	10.4	34.6	43.7
Choline, mg	0.9	3.3^†	10.8	13.7
Inositol, mg	1.7	5.4^†	18	22.7

Minerals
Calcium, mg	30	36	121	152
Calcium, mEq	1.5	1.8	6	7.6
Phosphorus, mg	17	20	67	85
Magnesium, mg	2.1	2.8	9.6	12.1
Iron, mg	0.11	0.14	0.47	0.59
Zinc, mg	0.31	0.39	1.32	1.66
Manganese, mcg	2.2	2.4^†	7.8	9.9
Copper, mcg	15	31	104	131
Iodine, mcg	0.4	3.1^†	10	13
Selenium, mcg	0.2	0.5^†	2	2
Sodium, mg	7.5	13.7	46	58
Sodium, mEq	0.3	0.6	1.9	2.4
Potassium, mg	16.2	30.4	102	128
Potassium, mEq	0.4	0.8	2.5	3.2
Chloride, mg	13	27	89	113
Chloride, mEq	0.4	0.8	2.6	3.3

INGREDIENTS: Water, corn maltodextrin, casein hydrolysate; LESS THAN 2% OF: M. alpina oil,^||schizochytrium sp. oil,^¶lutein, betacarotene, calcium phosphate, magnesium chloride, potassium citrate, sodium citrate, salt, potassium chloride, potassium phosphate, zinc sulfate, ferrous sulfate, copper sulfate, manganese sulfate, sodium selenite, medium chain triglycerides, soy oil, coconut oil, modified corn starch, vitamin A palmitate, vitamin D3, d-alphatocopheryl acetate, phylloquinone, thiamine hydrochloride, riboflavin, pyridoxine hydrochloride, vitamin B12, niacinamide, folic acid, calcium pantothenate, biotin, ascorbic acid, inositol, choline chloride, monoglycerides, L-tyrosine, L-leucine, L-tryptophan, L-carnitine, gellan gum, and potassium hydroxide.

CONTAINS MILK INGREDIENTS.

* One packet (5 mL) Similac Human Milk Fortifier Hydrolyzed Protein Concentrated Liquid in 25 mL preterm human milk (PTHM). Preterm human milk values from Meeting the Special Needs of Low-Birth-Weight and Premature Infants in the Hospital. Columbus, OH: Abbott Nutrition, Abbott Laboratories, January 1998.

^†Values based on term human milk from American Academy of Pediatrics Committee on Nutrition: Pediatric Nutrition Handbook, 4th ed. Elk Grove Village, American Academy of Pediatrics, 1998;40: 132-135, 217, 258, 655-658.

^‡ Per 100 Calories, as mixed, 4 packets added to 100 mL preterm human milk (24 Cal/fl oz). Preterm human milk values from Meeting the Special Needs of Low-Birth-Weight and Premature Infants in the Hospital. Columbus, OH: Abbott Nutrition, Abbott Laboratories, January 1998.

^§ When mixed with 25 mL term human milk, protein is 0.76 g and carbohydrate is 2.55 g/30 mL.

^|| Source of ARA.

^¶ Source of DHA.

Extensively Hydrolyzed Protein Concentrated Liquid

(SHMF HP CL) Nutrients per Volume

Nutrients	Per 5 mL packet	Per 30 mL PTHM (25 mL) + \|+ SHMF HP CL (1 packet)	Preterm Human Milk* (PTHM)	Per 100 mL PTHM (50 mL) + SHMF HP CL (1 packet)	PTHM (25 mL) + SHMF HP CL (1 packet)
Volume, mL	5	30	100	100	100
Energy, Cal	7	24	67	74	79
Protein, g	0.5	0.85^†	1.4	2.19	2.84
Fat, g	0.21	1.18	3.89	3.92	3.94
Linoleic Acid, mg	18	110	369.1	368	368
Carbohydrates, g	0.75	2.41^†	6.6	7.4	8.04

Vitamins
Vitamin A, IU	197	295	390	713	984
Vitamin D, IU	35	35.5	2	65	118.6
Vitamin E, IU	1	1.25	1.1	2.8	4.2
Vitamin K, mcg	2.4	2.5	0.2	4.5	8.3
Thiamin (Vit B1), mcg	48	53.3	20.8	106	178.0
Riboflavin (Vit B2), mcg	74.3	86.4	48.3	178	288.4
Vitamin B6, mcg	49.6	53.3	14.8	104	178.0
Vitamin B12, mcg	0.13	0.14	0.05	0.28	0.47
Niacin, mcg	980	1010	150	1918	3398
Folic Acid, mcg	6.86	7.7	3.3	15.7	25.7
Pantothenic Acid, mcg	310	355	181	728	1186
Biotin, mcg	5.82	5.9	0.4	10.9	19.8
Vitamin C, mg	7.74	10.4	10.7	23.8	34.8
Choline, mg	0.93	3.3	9.4	10.2	10.9
Inositol, mg	1.7	5.4	14.8	16.5	18.1

Minerals
Calcium, mg	29.8	36.0	24.8	77	120.2
Calcium, mEq	1.5	1.8	1.2	3.9	6.0
Phosphorus, mg	17.2	20.4	12.8	42.5	68.0
Magnesium, mg	2.1	2.8	3.1	6.6	9.8
Iron, mg	0.11	0.14	0.12	0.31	0.48
Zinc, mg	0.31	0.39	0.34	0.87	1.30
Manganese, mcg	2.2	2.4	0.6	4.5	7.9
Copper, mcg	14.7	30.8	64.4	85.8	102.7
Iodine, mcg	0.4	3.1	10.7	10.5	10.3
Sodium, mg	7.5	13.7	24.8	36	46
Sodium, mEq	0.3	0.6	1.1	1.5	1.9
Potassium, mg	16.2	36.4	57.0	81	102
Potassium, mEq	0.4	1.5	1.5	2.1	2.5
Chloride, mg	13	27.3	55	73.7	90.9
Chloride, mEq	0.4	0.8	1.6	2.1	2.6
Selenium, mcg	0.18	0.5	1.48	1.71	1.82

Other Characteristics
Potential Renal Solute Load, mOsm	4.5	7.7	12.6	19.6	25.5
Approx Osmolality, mOsm/kg water	-	450	290	375	450

NOTE: Proper hygiene, handling and storage are important when preparing infant feedings. Always follow your hospital’s policies and procedures regarding safe handling practices when preparing infant feedings to prevent the possibility of contamination.

* Meeting the special nutrient needs of low birth weight and premature infants in the hospital (A8100) Columbus, Ohio: Abbott Nutrition, Abbott, January 1998, p 56.

^† When mixed with 25 mL term human milk, protein is 0.76 g and carbohydrate is 2.55 g/30 mL.

Extensively Hydrolyzed Protein Concentrated Liquid

(SHMF HP CL) Nutrients per 100 Cal

NUTRIENTS	*Preterm Human Milk (PTHM)**	PTHM (50 mL) + SHMF HP CL (1 packet)	PTHM (25 mL) + SHMF HP CL (1 packet)
Energy, Cal	100	100	100
Volume, mL	149	136	126
Protein, g	2.1	2.97	3.58
Fat, g	5.8	5.32	4.98
Linoleic Acid, mg	550	499	464
Carbohydrates, g	9.9	10.04	10.14

Vitamins
Vitamin A, IU	581	966	1238
Vitamin D, IU	3.0	89	149
Vitamin E, IU	1.6	3.8	5.3
Vitamin K, mcg	0.3	6.2	10.3
Thiamin (Vit B1), mcg	31	144	224
Riboflavin (Vit B2), mcg	72	242	362
Vitamin B6, mcg	22	141	226
Vitamin B12, mcg	0.07	0.38	0.6
Niacin, mcg	224	2602	4279
Folic Acid, mcg	4.9	21.3	32.9
Pantothenic Acid, mcg	269	987	1494
Biotin, mcg	0.6	14.8	24.8
Vitamin C, mg	16.0	32.2	43.7
Choline, mg	14.0	13.8	13.7
Inositol, mg	22.0	22.4	22.7

Minerals
Calcium, mg	37.0	105	152
Calcium, mEq	1.9	5.2	7.6
Phosphorus, mg	19.0	58	85
Magnesium, mg	4.6	9	12.1
Iron, mg	0.18	0.42	0.59
Zinc, mg	0.51	1.19	1.66
Manganese, mcg	1	6.2	9.9
Copper, mcg	96.0	116	131
Iodine, mcg	16	14	13
Sodium, mg	37.0	49	58
Sodium, mEq	1.6	2.1	2.4
Potassium, mg	85.0	110	128
Potassium, mEq	2.2	2.8	3.2
Chloride, mg	82.0	100	113
Chloride, mEq	2.3	2.9	3.3
Selenium, mcg	2.2	2.3	2.4

Other Characteristics
Potential Renal Solute Load, mOsm	18.7	26.6	32.2
Approx Osmolality, mOsm/kg water	290	375	450

* Meeting the special nutrient needs of low birth weight and premature infants in the hospital (A8100) Columbus, Ohio: Abbott Nutrition, Abbott, January 1998, p 56.

Mixing Instructions, Use as directed by a doctor

Directions for Preparation and Use

This fortifier is for premature and low-birth-weight infants, including those infants <2000 g at hospital discharge. For post-discharge use, follow the doctor’s instructions as specified for your baby. Proper hygiene, handling, and storage are important when preparing fortified human milk. lmproper mixing may not meet your baby’s nutritional needs.

Additional Calories Desired	Human Milk	SHMF HP CL	Approximate Yield
2 Calories/fl oz	50 mL	1 packet	55 mL
4 Calories/fl oz	25 mL	1 packet	30mL

Follow instructions for safe handling of human milk. Consult with doctor on the need to boil (sterilize) bottles, nipples, and rings.

Pour desired quantity of human milk into sterile feeding container.

To open packet, tear top off completely along perforation.

Product separation is normal. Massage packet contents until uniform.

Add contents to human milk; cap and shake until mixed well. Once bottle-feeding begins, use within one hour or discard.

Storing Fortified Human Milk

• When more than one feeding is prepared, date and refrigerate unused portion; discard after 24 hours.

• After refrigeration, remix gently if needed. Feed promptly.

STORAGE

Product is light sensitive. Keep unopened packets in closed carton at room temperature; avoid extreme temperatures.

Warning

Never use a microwave oven to warm feedings. Serious burns can result.

WEBNOVA

Similac® Human Milk Fortifier

Extensively Hydrolyzed Protein Concentrated Liquid

(SHMF HP CL)

Nutrients

Per 5 mL SHMF HP CL packet

Per 30 mL* PTHM (25 mL) + SHMF HP CL (1 packet)

Per 100 mL PTHM (25 mL) + SHMF HP CL (1 packet)

Per 100 Cal‡ PTHM (25 mL) + SHMF HP CL (1 packet)

Vitamins

Minerals

Extensively Hydrolyzed Protein Concentrated Liquid

(SHMF HP CL) Nutrients per Volume

Nutrients

Per 5 mL packet

Per 30 mL PTHM (25 mL) + |+ SHMF HP CL (1 packet)

Preterm Human Milk* (PTHM)

Per 100 mL PTHM (50 mL) + SHMF HP CL (1 packet)

PTHM (25 mL) + SHMF HP CL (1 packet)

Vitamins

Minerals

Other Characteristics

Extensively Hydrolyzed Protein Concentrated Liquid

(SHMF HP CL) Nutrients per 100 Cal

NUTRIENTS

Preterm Human Milk* (PTHM)

PTHM (50 mL) + SHMF HP CL (1 packet)

PTHM (25 mL) + SHMF HP CL (1 packet)

Vitamins

Minerals

Other Characteristics

Mixing Instructions, Use as directed by a doctor

Directions for Preparation and Use

Storing Fortified Human Milk

STORAGE

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Similac^® Human Milk Fortifier

Per 100 Cal^‡ PTHM (25 mL) + SHMF HP CL (1 packet)

Per 30 mL
PTHM (25 mL) +
|+ SHMF HP CL
(1 packet)

Preterm Human Milk*
(PTHM)

Per 100 mL
PTHM (50 mL) +
SHMF HP CL
(1 packet)

PTHM (25 mL) + SHMF HP CL
(1 packet)

**Preterm Human Milk* (PTHM)**