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Similac® Human Milk Fortifier Hydrolyzed Protein Concentrated Liquid

Infant formula with extensively hydrolyzed protein

Similac® Human Milk Fortifier Hydrolyzed Protein Concentrated Liquid

Infant formula with extensively hydrolyzed protein

Intended for premature and low-birth-weight infants as a nutritional supplement to add to human milk.

Features:

  • Clinically shown to improve growth for your littlest patients1 
  • Extensively hydrolyzed for easy digestion and absorption
  • DHA for brain and eye development
  • Lutein to support eye development

 

Reference: 1. Kim JH, et al. J Pediatr Gastroenterol Nutr. 2015;61:665-671.

Clinical Information

Nutritional Information

Unflavored Concentrated Liquid - 5 mL (1 Packet)

Nutrient Data
Amount Per Serving
Calories 7
Volume, mL 5
Protein, g 0.5
Fat, g 0.21
Carbohydrate, g 0.75
Water, g 3.3
Linoleic Acid, mg 18
Potential Renal Solute Load, mOsm 4.5
Osmolality, mOsm/kg H2O NA
Vitamins
Amount Per Serving
Vitamin A, IU 197
Vitamin D, IU 35
Vitamin E, IU 1
Vitamin K, mcg 2.4
Thiamin (Vitamin B1), mcg 48
Riboflavin (Vitamin B2), mcg 74
Vitamin B6, mcg 50
Vitamin B12, mcg 0.13
Niacin, mcg 980
Folic Acid (Folacin), mcg 7
Pantothenic Acid, mcg 310
Biotin, mcg 5.8
Vitamin C (Ascorbic Acid), mg 7.7
Choline, mg 0.9
Inositol, mg 1.7
Minerals
Amount Per Serving
Calcium, mg 30
Calcium, mEq 1.5
Phosphorus, mg 17
Magnesium, mg 2.1
Iron, mg 0.11
Zinc, mg 0.31
Manganese, mcg 2.2
Copper, mcg 15
Iodine, mcg 0.4
Selenium, mcg 0.2
Sodium, mg 7.5
Sodium, mEq 0.3
Potassium, mg 16.2
Potassium, mEq 0.4
Chloride, mg 13
Chloride, mEq 0.4

Unflavored Concentrated Liquid - 30 mL (1 packet mixed with 25 mL preterm human milk)

Nutrient Data
Amount Per Serving
Calories 24
Volume, mL 30
Protein, g 0.85*
Fat, g 1.18
Carbohydrate, g 2.41*
Water, g 25.3
Linoleic Acid, mg 110†
Potential Renal Solute Load, mOsm 7.7
Osmolality, mOsm/kg H2O 450
Vitamins
Amount Per Serving
Vitamin A, IU 295
Vitamin D, IU 36
Vitamin E, IU 1.3
Vitamin K, mcg 2.5
Thiamin (Vitamin B1), mcg 53
Riboflavin (Vitamin B2), mcg 86
Vitamin B6, mcg 53
Vitamin B12, mcg 0.14
Niacin, mcg 1010
Folic Acid, mcg 8
Pantothenic Acid, mcg 355
Biotin, mcg 5.9†
Vitamin C (Ascorbic Acid), mg 10.4
Choline, mg 3.3†
Inositol, mg 5.4†
Minerals
Amount Per Serving
Calcium, mg 36
Calcium, mEq 1.8
Phosphorus, mg 20
Magnesium, mg 2.8
Iron, mg 0.14
Zinc, mg 0.39
Manganese, mcg 2.4†
Copper, mcg 31
Iodine, mcg 3.1†
Selenium, mcg 0.5†
Sodium, mg 13.7
Sodium, mEq 0.6
Potassium, mg 30.4
Potassium, mEq 0.8
Chloride, mg 27
Chloride, mEq 0.8

Unflavored Concentrated Liquid - 100 mL*

Nutrient Data
Amount Per Serving
Calories 79
Volume, mL 100
Protein, g 2.84
Fat, g 3.94
Carbohydrate, g 8.04
Water, g 84
Linoleic Acid, mg 368
Potential Renal Solute Load, mOsm 25.5
Osmolality, mOsm/kg H2O 450
Vitamins
Amount Per Serving
Vitamin A, IU 982
Vitamin D, IU 118
Vitamin E, IU 4.2
Vitamin K, mcg 8.2
Thiamin (Vitamin B1), mcg 177
Riboflavin (Vitamin B2), mcg 287
Vitamin B6, mcg 179
Vitamin B12, mcg 0.47
Niacin, mcg 3392
Folic Acid (Folacin), mcg 26.1
Pantothenic Acid, mcg 1184
Biotin, mcg 19.7
Vitamin C (Ascorbic Acid), mg 34.6
Choline, mg 10.8
Inositol, mg 18
Minerals
Amount Per Serving
Calcium, mg 121
Calcium, mEq 6
Phosphorus, mg 67
Magnesium, mg 9.6
Iron, mg 0.47
Zinc, mg 1.32
Manganese, mcg 7.8
Copper, mcg 104
Iodine, mcg 10
Selenium, mcg 2
Sodium, mg 46
Sodium, mEq 1.9
Potassium, mg 102
Potassium, mEq 2.5
Chloride, mg 89
Chloride, mEq 2.6

Unflavored Concentrated Liquid - 100 Cal (~4 packets mixed with 100 mL preterm human milk)

Nutrient Data
Amount Per Serving
Calories 100
Volume, mL 126
Protein, g 3.58
Fat, g 4.98
Carbohydrate, g 10.14
Water, g 106
Linoleic Acid, mg 464
Potential Renal Solute Load, mOsm 32.2
Osmolality, mOsm/kg H2O 450
Vitamins
Amount Per Serving
Vitamin A, IU 1238
Vitamin D, IU 149
Vitamin E, IU 5.3
Vitamin K, mcg 10.3
Thiamin (Vitamin B1), mcg 224
Riboflavin (Vitamin B2), mcg 362
Vitamin B6, mcg 226
Vitamin B12, mcg 0.6
Niacin, mcg 4279
Folic Acid, mcg 32.9
Pantothenic Acid, mcg 1494
Biotin, mcg 24.8
Vitamin C (Ascorbic Acid), mg 43.7
Choline, mg 13.7
Inositol, mg 22.7
Minerals
Amount Per Serving
Calcium, mg 152
Calcium, mEq 7.6
Phosphorus, mg 85
Magnesium, mg 12.1
Iron, mg 0.59
Zinc, mg 1.66
Manganese, mcg 9.9
Copper, mcg 131
Iodine, mcg 13
Selenium, mcg 2
Sodium, mg 58
Sodium, mEq 2.4
Potassium, mg 128
Potassium, mEq 3.2
Chloride, mg 113
Chloride, mEq 3.3

Similac® Human Milk Fortifier Hydrolyzed Protein Concentrated Liquid

Clinical study shows improved growth for your littlest babies.1,* Extensively hydrolyzed protein for easy digestion and absorption. Non-acidified. Lutein and DHA for developing eyes and brain. When added to human milk, meets expert recommendations for protein2,3,† and other nutrients for the preterm infant.2 Preterm human milk values from "Meeting the Special Needs of Low-Birth-Weight and Premature Infants in the Hospital", Columbus, OH, Abbott Nutrition, Abbott Laboratories, Jan 1998. Well tolerated. Small, convenient packet is designed for easy mixing. Commercially sterile and meets the AND and CDC recommendation to use liquid for NICU feedings.4,5,‡ Low iron level provides flexibility to add iron as needed. Gluten-free.

  • * Compared to control HMF.
  • † One packet mixed with 25 mL of human milk.
  • ‡ Academy of Nutrition and Dietetics and Centers for Disease Control and Prevention.
  • 1 Kim JH, et al. J Pediatr Gastroenterol Nutr. 2015;61-665-71.
  • 2 Koletzko B, et al. Nutritional Care of Preterm Infants. Scientific Basis and Practical Guidelines. World Rev Nutr Diet. Basel, Karger, 2021, vol 122 pp 191-197.
  • 3 Agostoni C, et al. JPGN. 2010;58:85-91.
  • 4 Centers for Disease Control and Prevention. Enterobacter sakazakii infections associated with the use of powdered infant formula—Tennessee, 2001. Available at http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5114a1.htm. Published April 11, 2002. Accessed November 27, 2019.
  • 5 Steele C, Collins E (eds). Infant and Pediatric Feedings: Guidelines for Preparation of Human Milk and Formula in Health Care Facilities, 3rd Ed. Academy of Nutrition and Dietetics. 2019.

Ingredients

Unflavored Concentrated Liquid

Water, Corn Maltodextrin, Casein Hydrolysate. Less than 2% of: M. Alpina Oil*, Schizochytrium Sp. Oil†, Lutein, Beta-Carotene, Calcium Phosphate, Magnesium Chloride, Potassium Citrate, Sodium Citrate, Salt, Potassium Chloride, Potassium Phosphate, Zinc Sulfate, Ferrous Sulfate, Copper Sulfate, Manganese Sulfate, Sodium Selenite, Medium Chain Triglycerides, Soy Oil, Coconut Oil, Modified Corn Starch, Vitamin A Palmitate, Vitamin D3, dl-Alpha-Tocopheryl Acetate, Phylloquinone, Thiamine Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Vitamin B12, Niacinamide, Folic Acid, Calcium Pantothenate, Biotin, Ascorbic Acid, Inositol, Choline Chloride, Monoglycerides, L-Tyrosine, L-Leucine, L-Tryptophan, L-Carnitine, Gellan Gum, and Potassium Hydroxide.
* Source of ARA.
† Source of DHA.

Resources

Precautions

Add only to human milk - do not add water.

This product is nutritionally incomplete by itself and is designed to be added to human breast milk.

Additional iron may be necessary.

Tolerance to enteral feedings should be confirmed by offering small volumes of unfortified human milk.

Once enteral feeding is well established, Similac Human Milk Fortifier Hydrolyzed Protein Concentrated Liquid can be added to human milk.

Never use a microwave oven to warm feedings. Serious burns can result.

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